Both coffee and Doxycycline are capable of scavenging multiple reactive oxygen species, thus providing significant antioxidant activity. If you feel better after ingesting either one, it could be because of increased oxidative stress in your body.

Many factors can stress the kidneys, such as heavy metals, infections, detox programs, and mold (mycotoxins). Low nitric oxide levels can contribute to kidney stress. Resveratrol is known for its heart-protective benefits, and this is why red wine, in moderation, is often linked to heart health. Reducing caffeine intake is also important, as it can inhibit nitric oxide production and put extra stress on the kidneys.