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Herxheimer Reactions - What Exactly Are They ?
Understanding the mechanics of Herxheimer reactions can give us clues about what may be causing them and how to limit them during detoxification.
What Is With Food In The U.S. ?
Herbicides and pesticides are commonly used in the food supply chain in the United States that are banned in other countries. Could this be behind some of feel better when we travel over-seas ?
Novel Ways To Engage The Parasympathetic Nervous System
Understanding different fast acting ways to help regulate your nervous system, engage the parasympathetic branch of your nervous system, improve your sleep and HRV.
The Many Faces Of Schisandra, from Detoxification, Lipid Metabolism, and Acetyl-Aldehyde
Schisandra is an herb long used in chinese medicine - for cholesterol, and triglyceride improvement. Learn the detailed effects by Schisandra on lipid metabolism, acetyl aldehyde clearance, detoxification, and anti oxidant genes.
Copper: Immune, Anti-Oxidant, and Virulence Considerations
Copper is an important nutrient used as a cofactor is genes associated with anti oxidant systems, and immune function to name a couple. Copper also, has specific considerations to help absorption, as well as toxicity in excess.
GPX4 - Glutathione Peroxidase4, Located Exclusively In the Mitochondria
GPX4 - Glutathione Peroxidase4, is the only glutathione peroxidase gene located exclusively in the mitochondria. It takes the exhaust products of SOD2, hydrogen peroxide, and turns it into water. If mutated, inhibited, or non functioning, GPX4, can lead to ferroptosis - unmitigated cell death.
Andrographis - Anti Inflammatory, Anti Viral and Anti Microbial
Andrographis is an herb commonly used to treat colds and respiratory infections, but also has many other potential applications. Andrographis is a potent inhibitor of NOS2, regulates inflammatory genes like NFKB, NLPR3, TNFA, and also induces Heat Shock Protein 70 (HSP70) increases cellular resistance to oxidative and thermal stress.
Arg1 - Important for Clearing Arginine and Ammonia that Can Cause Brain Fog
Arg1 is a key gene needed in the urea cycle to clear ammonia which can cause brain fog. There are many common herbs used in various anti inflammatory and anti oxidant therapies that inhibit Arg1. If you suffer from brain fog, this article may be interesting to explore.
Low Iron / Anemia of Inflammation (High IL-6)- By Activation Of Hepcidin. Cobalt and Aluminum Effects On Iron Homeostasis
Anemia of inflammation is a common condition experienced by those who suffer from chronic illnesses, such as mold exposure, ME / CFS, or Long Covid. Elevations in Hepcidin, induced by elevations in the inflammatory marker IL-6, lower absorption of dietary iron.
The French Paradox - Red Wine, OX-LDL, Resveratrol, and Procyanidins
Cardiovascular disease continues to be a primary issue in many countries. This article explores some of the mechanics behind arterial wall plaque formation and why the French seem to have some sort of protection from high fat diets.
Golf Courses, Bats, Guam, Parkinson’s, Cyanobacteria, BMAA, Alzheimer’s, ALS, and L-Serine…..What is Going On?
Interesting studies provide clues on some of the potential contributing factors to neurological disorders like Alzheimer’s, Parkinsons, and ALS. Recent studies link proximity to golf courses at risk for Parkinsons. Meanwhile, links to Cyanobacteria and BMAA toxicity due to bat consumption in Guam also provide clues on the cascade dysfunction that leads to neurological disorders.
Inner Membrane of the Mitochondria: SS-31
The inner membrane of the mitochondria, is home to cardiolipin, a very special component.
NQO1: Quinone oxidoreductase 1 (Draft)
NQO1 is a critical gene performing a variety of functions from detoxification of volatile organic compounds, recycling NAD and coQ10, neutralizing super oxide, and recycling NAD/NADPH.
DIY: Home Filter Options
Home air filter systems can be a valuable addition to our lives and homes to ensure the air we breathe has less of a toxin load. In this article, i discuss, how to do this on the cheap, using a box fan and home furnace filters.
Blue Zone Diets (Part 1) - And Alzheimer’s Disease
The Blue Zone Diets. Why folks in Blue Zones have lower rates of dimentia and Alzheimers. Serine and PHGDH. Read on.
SULT Genes (1A1) : Sulfur Issues Again
SULT genes, principally SULT1A1, are used in the detoxification of many compounds. Its also at the cross-roads for sulfur related issues for many.