Riboflavin is a critical nutrient used in many different systems: anti oxidant, heme synthesis, neurotransmitter metabolism, detoxification, mitochondria energy production, and activation of other vitamins like B6 to name just a few.

Kutki, a plant that is a source of Apocynin’s offers significant benefits in lowering oxidative stress, and protecting against neuro degeneration.

All about the 8 different forms of Vitamin E - Tocotrienols and Tocopherols. Each of the 4 types of Tocotrienols and 4 types of Tocopherols offer unique benefits. From protecting against nitrative stress, neural protection, mitochondrial benefits, or cholesterol lowering effects - each plays a special role.

Glutathione is often considered the master anti oxidant - but it also plays other key roles too, as an important cofactor, and an immune regulator.

Some basic facts around methylation, the prevalence of mutations on MTHF1298c and MTHFR C677T.

Biotin deficiency and the connections to candida, diet, genetics, and stress.

Understanding the mechanics of Herxheimer reactions can give us clues about what may be causing them and how to limit them during detoxification.

Herbicides and pesticides are commonly used in the food supply chain in the United States that are banned in other countries. Could this be behind some of feel better when we travel over-seas ?

Understanding different fast acting ways to help regulate your nervous system, engage the parasympathetic branch of your nervous system, improve your sleep and HRV.

Schisandra is an herb long used in chinese medicine - for cholesterol, and triglyceride improvement. Learn the detailed effects by Schisandra on lipid metabolism, acetyl aldehyde clearance, detoxification, and anti oxidant genes.

Copper is an important nutrient used as a cofactor is genes associated with anti oxidant systems, and immune function to name a couple. Copper also, has specific considerations to help absorption, as well as toxicity in excess.

GPX4 - Glutathione Peroxidase4, is the only glutathione peroxidase gene located exclusively in the mitochondria. It takes the exhaust products of SOD2, hydrogen peroxide, and turns it into water. If mutated, inhibited, or non functioning, GPX4, can lead to ferroptosis - unmitigated cell death.

Andrographis is an herb commonly used to treat colds and respiratory infections, but also has many other potential applications. Andrographis is a potent inhibitor of NOS2, regulates inflammatory genes like NFKB, NLPR3, TNFA, and also induces Heat Shock Protein 70 (HSP70) increases cellular resistance to oxidative and thermal stress.

Arg1 is a key gene needed in the urea cycle to clear ammonia which can cause brain fog. There are many common herbs used in various anti inflammatory and anti oxidant therapies that inhibit Arg1. If you suffer from brain fog, this article may be interesting to explore.

Anemia of inflammation is a common condition experienced by those who suffer from chronic illnesses, such as mold exposure, ME / CFS, or Long Covid. Elevations in Hepcidin, induced by elevations in the inflammatory marker IL-6, lower absorption of dietary iron.

Cardiovascular disease continues to be a primary issue in many countries. This article explores some of the mechanics behind arterial wall plaque formation and why the French seem to have some sort of protection from high fat diets.