Jump to Research About:
Biotin Deficiency: Impaired Heme Synthesis, Loss of Mitochondrial Complex IV , and Oxidative Stress
Biotin deficiency and the connections to candida, diet, genetics, and stress.
Novel Ways To Engage The Parasympathetic Nervous System
Understanding different fast acting ways to help regulate your nervous system, engage the parasympathetic branch of your nervous system, improve your sleep and HRV.
Copper: Immune, Anti-Oxidant, and Virulence Considerations
Copper is an important nutrient used as a cofactor is genes associated with anti oxidant systems, and immune function to name a couple. Copper also, has specific considerations to help absorption, as well as toxicity in excess.
GPX4 - Glutathione Peroxidase4, Located Exclusively In the Mitochondria
GPX4 - Glutathione Peroxidase4, is the only glutathione peroxidase gene located exclusively in the mitochondria. It takes the exhaust products of SOD2, hydrogen peroxide, and turns it into water. If mutated, inhibited, or non functioning, GPX4, can lead to ferroptosis - unmitigated cell death.
Andrographis - Anti Inflammatory, Anti Viral and Anti Microbial
Andrographis is an herb commonly used to treat colds and respiratory infections, but also has many other potential applications. Andrographis is a potent inhibitor of NOS2, regulates inflammatory genes like NFKB, NLPR3, TNFA, and also induces Heat Shock Protein 70 (HSP70) increases cellular resistance to oxidative and thermal stress.
Low Iron / Anemia of Inflammation (High IL-6)- By Activation Of Hepcidin. Cobalt and Aluminum Effects On Iron Homeostasis
Anemia of inflammation is a common condition experienced by those who suffer from chronic illnesses, such as mold exposure, ME / CFS, or Long Covid. Elevations in Hepcidin, induced by elevations in the inflammatory marker IL-6, lower absorption of dietary iron.
Inner Membrane of the Mitochondria: SS-31
The inner membrane of the mitochondria, is home to cardiolipin, a very special component.
NQO1: Quinone oxidoreductase 1 (Draft)
NQO1 is a critical gene performing a variety of functions from detoxification of volatile organic compounds, recycling NAD and coQ10, neutralizing super oxide, and recycling NAD/NADPH.
SULT Genes (1A1) : Sulfur Issues Again
SULT genes, principally SULT1A1, are used in the detoxification of many compounds. Its also at the cross-roads for sulfur related issues for many.
Chrysin (Often extracted from Passion Flower)
Chrysin, extracted from Passion Flower, was a topic a Long Haul Covid Clinics Webinar series. I wanted to add some things to provide a more accurate context about its mechanisms of action.
Magnesium, Epsom Salt Baths, & The Production of NAD+ and Reduction of Neurotoxic Quinolinic Acid
Many use epsom salt baths to ‘relax and recharge’, or simply help our mind become less stressed. What is going, why is this happening ? We will explore the NAD+/NADPH pathway, magnesium, the QPRT gene, quinolinic acid, and one of many reasons why oxidative stress matters (alot).
The Wonders of Proanthocyanidins: Marine Pine Bark, Pycnogenol, Grape Seed Extract, and Red Rice Germ
Sources of proanthocyanidins like Pycnogenol, Pine Bark, Grape Seed Extract, and Red Rice Bran offer a wide range of significant health benefits. These benefits range across a variety of areas from circulation, oxidative stress, inflammation, and gut microbiome benefits.
Herbal Approaches To Modulating iNOS, IL-6, TNFA, COX-2, and IL-10
Learn how to use your herbs and spices to modulate key inflammatory and immune pathways. What to look out for to prevent inhibition of key immune genes like IL-10 on a long term basis.
Do You Feel Good on Coffee or Doxycycline? It May Be a Clue!
Both coffee and Doxycycline are capable of scavenging multiple reactive oxygen species, thus providing significant antioxidant activity. If you feel better after ingesting either one, it could be because of increased oxidative stress in your body.
Low Vitamin D: Ties To Osteoporosis and Biological Age
Understanding what are body needs to digest and process Vitamin D so it can be converted into useable forms is no simple process. Many cofactor nutrients are needed in addition to solid digestive health. Some of these are B2, B3, B6, B7, B12, Zinc, Copper, Manganese, Molybdenum, Selenium, Iodine, Lipoic Acid, Glycine, and more.
Fucoidan: The Magic of Brown Seaweed
The health benefits associated with Brown Seaweed, and one of its principal components - Fucoidan - are astounding. Known as an anticoagulant and potent anti-oxidant, there are many other benefits as well.