GPX4 - Glutathione Peroxidase4, is the only glutathione peroxidase gene located exclusively in the mitochondria. It takes the exhaust products of SOD2, hydrogen peroxide, and turns it into water. If mutated, inhibited, or non functioning, GPX4, can lead to ferroptosis - unmitigated cell death.

Many use epsom salt baths to ‘relax and recharge’, or simply help our mind become less stressed. What is going, why is this happening ? We will explore the NAD+/NADPH pathway, magnesium, the QPRT gene, quinolinic acid, and one of many reasons why oxidative stress matters (alot).

For middle aged folks, nothing can be more frightening than the looming prospect of cognitive decline and the potential of Alzheimer’s Disease and Neuro Degeneration.

Both coffee and Doxycycline are capable of scavenging multiple reactive oxygen species, thus providing significant antioxidant activity. If you feel better after ingesting either one, it could be because of increased oxidative stress in your body.

Ochratoxin A negatively impacts a significant number of pathways related to detoxification, oxidative stress, heme biosynthesis, and iron regulation. Research has shown that many commonly available compounds can help counteract these negative effects.

Ochratoxin A is a ubiquitous mold toxin (mycotoxin), and it is present in relatively low amounts in grains, nuts, legumes, teas, coffees, and root vegetables. Because it is also commonly found in water damaged buildings, and it is one of the most frequently recovered toxins in urine-based mycotoxin testing from Mosaic, Real Time Labs, and Vibrant America. It is linked to organ damage, neuroinflammation, and oxidative stress.