Riboflavin is a critical nutrient used in many different systems: anti oxidant, heme synthesis, neurotransmitter metabolism, detoxification, mitochondria energy production, and activation of other vitamins like B6 to name just a few.

Glutathione is often considered the master anti oxidant - but it also plays other key roles too, as an important cofactor, and an immune regulator.

Understanding the mechanics of Herxheimer reactions can give us clues about what may be causing them and how to limit them during detoxification.

NQO1 is a critical gene performing a variety of functions from detoxification of volatile organic compounds, recycling NAD and coQ10, neutralizing super oxide, and recycling NAD/NADPH.