Interesting studies provide clues on some of the potential contributing factors to neurological disorders like Alzheimer’s, Parkinsons, and ALS. Recent studies link proximity to golf courses at risk for Parkinsons. Meanwhile, links to Cyanobacteria and BMAA toxicity due to bat consumption in Guam also provide clues on the cascade dysfunction that leads to neurological disorders.

The inner membrane of the mitochondria, is home to cardiolipin, a very special component.

NQO1 is a critical gene performing a variety of functions from detoxification of volatile organic compounds, recycling NAD and coQ10, neutralizing super oxide, and recycling NAD/NADPH.

The Blue Zone Diets. Why folks in Blue Zones have lower rates of dimentia and Alzheimers. Serine and PHGDH. Read on.

SULT genes, principally SULT1A1, are used in the detoxification of many compounds. Its also at the cross-roads for sulfur related issues for many.

Chrysin, extracted from Passion Flower, was a topic a Long Haul Covid Clinics Webinar series. I wanted to add some things to provide a more accurate context about its mechanisms of action.

Many use epsom salt baths to ‘relax and recharge’, or simply help our mind become less stressed. What is going, why is this happening ? We will explore the NAD+/NADPH pathway, magnesium, the QPRT gene, quinolinic acid, and one of many reasons why oxidative stress matters (alot).

Sources of proanthocyanidins like Pycnogenol, Pine Bark, Grape Seed Extract, and Red Rice Bran offer a wide range of significant health benefits. These benefits range across a variety of areas from circulation, oxidative stress, inflammation, and gut microbiome benefits.

Learn how to use your herbs and spices to modulate key inflammatory and immune pathways. What to look out for to prevent inhibition of key immune genes like IL-10 on a long term basis.

Morning Blue Light Therapy has long standing notable published research that it helps TBI patients improve, and more recently Alzheimer’s patients improve cognitive function, while also activating brain circuits associated with Glymphatic Drainage by modulating Aquaporin-4.

Understanding what are body needs to digest and process Vitamin D so it can be converted into useable forms is no simple process. Many cofactor nutrients are needed in addition to solid digestive health. Some of these are B2, B3, B6, B7, B12, Zinc, Copper, Manganese, Molybdenum, Selenium, Iodine, Lipoic Acid, Glycine, and more.

The health benefits associated with Brown Seaweed, and one of its principal components - Fucoidan - are astounding. Known as an anticoagulant and potent anti-oxidant, there are many other benefits as well.

Key health considerations for high dose vitamin c therapy include health of anti oxidant systems, state of oxidative stress load, iron status, oxalate status, and if helps is needed to recycle BH4 and methylfolate.

Mycotoxin exposure is synonymous with chronic illness, ME / CFS, and Long Haul Covid. Approximately 50-75% of the folks that find me test over the 95% for at least one mycotoxin. Mycotoxins cause organ damage, oxidative stress, neurodegeneration, and some lead to blood glucose issues and diabetes, while others cause iron dysregulation and low ferritin.

Heme is one of the most common cofactors in the body needed for : All Phase I CYP450 enzymes, Nitic Oxide, Catalase, Glutathione Peroxidase, Super Oxide Dismutase, Electron Transport In Complexes II, III, IV, Cytochrome C, SUOX (Sulfur), Tryptophan metabolism, and NAD/NADPH synthesis. Some of the more extreme symptoms include sensitivity to sunlight, gall bladder attacks and strange abdominal pain, skin lesions and acute neurovisceral attacks, and alcohol sensitivity. Deficiencies in the required cofactors such as : B2, B6, B7, B12, Lipoic Acid, Glycine, Succinyl Co A, Zinc, Copper, or Iron can disrupt heme biosynthesis. Critically impacted in hypoxic conditions, as well as by oxidative stress and toxic gut metabolites like acetyl aldehydes and hydrogen sulfide.

Ochratoxin A is a ubiquitous mold toxin (mycotoxin), and it is present in relatively low amounts in grains, nuts, legumes, teas, coffees, and root vegetables. Because it is also commonly found in water damaged buildings, and it is one of the most frequently recovered toxins in urine-based mycotoxin testing from Mosaic, Real Time Labs, and Vibrant America. It is linked to organ damage, neuroinflammation, and oxidative stress.